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Volume 31 , Issue 3
May/June 2011
Pages 285-295

Quantitative Evaluation of Extraction Socket Healing Following the Use of Autologous Platelet-Rich Fibrin Matrix in Humans

Barry I. Simon, DDS, MSD/Priyu Gupta, DDS/Shereen Tajbakhsh, DDS

PMID: 21556385
DOI: 10.11607/prd.00.0983

Platelet-rich fibrin matrix (PRFM) is an autologous biologic material created by centrifugation of blood. This study quantified ridge changes associated with the healing of 21 extraction sites using PRFM alone as a graft. Standardized measurements of ridge width and height were recorded at extraction, after graft placement, and after 4 months of healing. Mean width resorption 3 and 5 mm apical to the crest was 0.32 mm (4.71% loss) and 0.57 mm (7.38% loss), respectively. Mean height resorption was 0.67 mm (7.13% loss). Sites grafted with PRFM alone displayed rapid clinical healing, minimal flap reopening, and excellent bone density. Advantages of PRFM alone include less surgical time, elimination of techniques and potential healing difficulties associated with membranes, and less resorption during healing, as compared to guided bone regeneration procedures. (Int J Periodontics Restorative Dent 2011;31:285–295.)

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